ProductDescription:
LyophilizedGingisKHAN(KGP)fordigestionof2mgofhumanIgG1togetherwith5vialsoflyophilizedGingisKHANreducingagentandfourCH1microspincolumnswhereeachcolumnincludessufficientmaterialtopurifyupto0.5mgIgG.
GingisKHAN(KGP)isauniqueproteasethatcleaveshumanIgG1atonesingleaminoacidpositionjustabovethehingeregiongeneratingintactFcandFabfragments.
Theenzymerequireverymildreducingreactionconditionsandforconvenieceandreliableperformance,theproductisprovidedwith5vialsoflyophilizedGingisKHANreducinagent.Theenzymeandreducitonagentarereconstitutedbyadditionofwater.
TheCH1affinitymatrixrecognizestheCH1domainofhumanIgGantibodies,whichenablespurificationofFabfragments,independentofthelight-chainisotypeandsourcematerial.DuetoitsuniqueselectivityfortheCH1domain,noco-purificationoffreelight-chaincontaminantswilloccur.
